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Research Paper | Obstetrics and Gynecology | India | Volume 12 Issue 2, February 2023 | Popularity: 5.1 / 10
Association of Endometrial Thickness with Incidence of Ectopic Pregnancy after Freeze - Thaw Transfer
Dr. Ananthi Babu
Abstract: Objective: To investigate whether endometrial thickness (EMT) influences the incidence of ectopic pregnancy (EP) in frozen embryo transfer (FET) cycles. Design: Retrospective cohort study. Setting Single center study. Methods A total of 606 pregnancy cycles after freeze ?thaw embryo transfer were included with number of intrauterine and ectopic pregnancies being 182 and 24 respectively. Main Outcome Measure EP was the primary outcome. EMT was the main measured variable. Result: 1. After adjusting for confounders, endometrial thickness could independently predict ectopic pregnancy. The adjusted odd ratios for women with endometrial thickness in the ranges of < 8mm, 8 - 9.9mm, and 10 - 11.9mm were 3.2702, 2.758 and 1.456 respectively, when compared with those having an endometrial thickness of 12 - 13.9mm.2. Endometrial type and preparation protocol were however not identified as risk factors for ectopic pregnancy. Discussion: 1. After freeze - thaw embryo transfer risks of ectopic pregnancy were significantly higher when the endometrial thickness was < 8 mm.2. A thin endometrial thickness could be linked with abnormal endometrial peristaltic waves or abnormal endometrial receptivity.3. Adequate attention should therefore be paid to patients with a thin endometrial thickness to prevent EP or to achieve early diagnosis during the peri - transplantation period. Conclusion: EMT is inversely proportional to EP rate in FET cycles and is therefore a potential quantitative marker of endometrial receptivity and uterine contractibility in an FET cycle. The predictive validity of EMT value must be evaluated in further studies.
Keywords: EMT, blastocyst, ectopic pregnancy, FET
Edition: Volume 12 Issue 2, February 2023
Pages: 943 - 945
DOI: https://www.doi.org/10.21275/SR23214181546
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