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Research Paper | Pathology | India | Volume 12 Issue 3, March 2023 | Rating: 5.4 / 10
Cytohistopathological Study of Salivary Gland Lesions in a Tertiary Care Hospital
Dr. Parita Patel | Dr. Pruthvi Patel
Abstract: Background: Due to its low cost, quick turnaround time, high specificity, and sensitivity, fine needle aspiration cytology (FNAC) is a useful procedure for assessing suspected salivary gland lesions. Salivary gland lesions are still best assessed by a histopathological analysis of the tissue that has been removed from the affected glands. Aim and objectives: 1) To evaluate the cyto-histopathological spectrum of salivary gland lesions.2) To find out the correlation of cytological findings from FNAC with histopathological diagnosis of salivary gland lesions. Methods and Material: Between January 2021 and June 2022, a one and a half year period, 35 patients with salivary glands swelling included in this study. A 10 mL disposable syringe and a 23/24-gauge needle were used during FNA procedures without the use of local anaesthesia from different sites of the salivary gland swelling. Haematoxylin and eosin staining of paraffin-embedded tissue slices taken from salivary gland tissue was performed. Results: Total 35 cases studied in which 21 were male and 14 were female (M: F = 1.5: 1). Age of patients ranged from 11 years to 84 years. Commonest gland involved was parotid (77.14%). According to the cyto-histological diagnosis, commonest benign neoplasm was pleomorphic adenoma. Amongst malignant neoplasms most common was mucoepidermoid carcinoma (2/35, 5.71%) and malignant epithelial neoplasms (2/35, 5.71%) on cytology. Total (22.86%) cases were diagnosed as malignant neoplasm on histopathology. Most common malignant tumour was mucoepidermoid carcinoma (8.57%). Conclusion: With sufficient sampling and an experienced cytopathologist, the majority of salivary gland lesions can be accurately diagnosed using FNA.
Keywords: Salivary gland, FNAC, Histopathology, Pleomorphic adenoma, Mucoepidermoid carcinoma
Edition: Volume 12 Issue 3, March 2023,
Pages: 258 - 261