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Case Studies | Medical Science | India | Volume 12 Issue 4, April 2023 | Rating: 4.3 / 10
Post Varicella Axonal Polyneuropathy: An Unusual Complication
Kamal Kumar Meher | Rama Krushna Sabat | Taranisen Sethi [2]
Abstract: 32-year-old female presented with two months history of gradually progressive symmetric distal quadriparesis associated with atrophy of both hands and tingling sensations. Patient was having past history of varicella 2weeks preceding the illness. On neurological examination patient was having wasting of small muscles of both hands, diminished power in distal group of muscles in all four limbs, DTRs were normal with normal tone and intact sensation along with bilateral plantar flexor response. Routine investigations were normal including LFT and RFT. IgG antibody titre to VZ virus was positive. There was no significant spinal cord compression on MRI cervical spine and MRI brachial plexus was normal. Nerve conduction study was suggestive of axonal polyneuropathy. After receiving oral acyclovir and IV methylprednisolone there was gradual improvement of symptoms. Although axonal polyneuropathy is an uncommon complication of herpes zoster it should be considered in a case of quadriparesis.
Keywords: varicella zoster, axonal polyneuropathy, dorsal root ganglion, anterior horn cells, segmental myelitis
Edition: Volume 12 Issue 4, April 2023,
Pages: 353 - 354