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Case Studies | Medical Science | Indonesia | Volume 12 Issue 4, April 2023 | Rating: 4.2 / 10

Pneumocystis Jirovecii Pneumonia (PCP) in HIV Patient: A Case Report

Dr. I Gst Ag Ayu Ratih Pradnyadewi | Dr. A. A Gde Upeksha

Abstract: Pneumocystis jirovecii pneumonia (PCP) caused by the Pneumocystis jirovecii fungus is an opportunistic infection that often manifests itself in Human Immunodeficiency Virus (HIV) patients. PCP is responsible for two - thirds of disease in the AIDS and estimated 75% of HIV - infected patients will develop PCP during their lifetime. The diagnosis of PCP is relatively difficult because the symptoms, blood tests, and chest radiography are not pathognomonic for PCP. Untreated PCP can be fatal and increase mortality. The main choice of PCP treatment is Trimethoprim - sulfamethoxazole (TMP - SMX) orally or intravenously for 21 days which is a combination of 2 enzyme inhibitors on pneumocystis folate synthesis. The severity of the infection and the high mortality rate in PCP make prevention very important in at - risk groups. This case report discusses a patient with complaints of fever, non - productive cough, and shortness of breath who was diagnosed with PCP. The patient received treatment in the form of cotrimoxazole 3x960 dose for 21 days. Treatment response was achieved on the seventh day and then the patient could go on an outpatient basis.

Keywords: Human Immunodeficiency Virus, HIV, Pneumocystis jirovecii pneumonia, PCP, Trimethoprim sulfamethoxazole, TMP SMX

Edition: Volume 12 Issue 4, April 2023,

Pages: 1778 - 1780