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Case Studies | Obstetrics and Gynecology | India | Volume 12 Issue 4, April 2023 | Rating: 4.7 / 10
Malignant Transformation in a Dermoid Cyst: Case Report
Dr. Prajakta Unde | Dr. Nitin Pai Dhungat | Dr. Shivani Agrawal
Abstract: Dermoid cyst (mature cystic teratoma) consists of well differentiated derivatives of three germ cell layers. They account for 20 % of all ovarian tumors. In its pure form these tumours are invariably benign in 95 % cases with wide age distribution. However as a rare complication malignant transformation may occur in approximately 1-2 % dermoid cysts. Most common malignancy being squamous cell carcinoma (SCC). Clinically malignant transformation cannot be identified readily as the diagnostic accuracy of ultrasound, MRI and CT is still debated. We report a case of this rare condition to highlight the features such a rapid increase in size, age >45 years, serum marker assays, some sonographic & radiological findings which should raise suspicion of malignancy when dermoids are encountered to help to make appropriate decision for choice of surgery & to ensure the correct staging of tumor so that appropriate post operative adjuvant chemotherapy is prescribed in an attempt to improve the poor prognosis.
Keywords: dermoid cyst, malignant transformation, squamous cell carcinoma
Edition: Volume 12 Issue 4, April 2023,
Pages: 1639 - 1641