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Analysis Study Research Paper | Microbiology | India | Volume 12 Issue 4, April 2023 | Rating: 5 / 10

Antibiotic Sensitivity Pattern of Bacterial Isolates from Respiratory Samples of Patients with Respiratory Tract Infection in a Tertiary Care Teaching Hospital of Pune: A Hospital Record-Based Study

Lt Col (Dr) Manas Dixit | Maj (Dr.) Neha Singh | Surg Cdr (Dr) Muzafar Ahmad Bhat | Dr Richa Jaiswal | Lt Col (Dr) Prashant Patil

Abstract: Background: Antibiotics are frequently used for various infectious diseases like acute lower respiratory tract infection (LRTI). Injudicious use of antibiotics often leads to antibiotic resistance which is an emerging problem worldwide. The objective of this study was taken up to analyse the antimicrobial sensitivity pattern of pathogens isolated from the respiratory samples of patients admitted with symptoms of acute LRTI in a tertiary care teaching hospital. Objective: To study the Antibiotic sensitivity pattern of bacterial isolates from respiratory samples of patients with respiratory tract infection. Method: This study was a hospital record based retrospective study of 243 patients. Result: Klebsiella pneumoniae was the most common organism isolated followed by Pseudomonas aeruginosa and Acinetobacter baumannii. Klebsiella pneumoniaewas most sensitive to Colistin and Doripenem. Pseudomonas aeruginosa and Acinetobacter baumannii were most sensitive to Colistin, Amikacin, Aztreonam, Trimethoprim / Sulfamethoxazole. Conclusion: The study highlights the extent of antibiotic resistance in common respiratory pathogens isolated from the respiratory samples.

Keywords: Antibiotic resistance, Klebsiella, Acinetobacter, Lower respiratory tract infection

Edition: Volume 12 Issue 4, April 2023,

Pages: 1817 - 1820