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Research Paper | Obstetrics and Gynecology | India | Volume 12 Issue 5, May 2023 | Popularity: 4.9 / 10

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Role of Mifepristone in Pre - Labor Cervical Ripening and Induction of Labour

Dr. Shivika Mittal, Dr. Rita Mittal, Dr. Prashant Dhatwalia

Abstract: Objective: To assess the efficacy of Mifepristone for pre labor cervical ripening and induction of labor. Material and methods: This study was conducted in the department of OBG in DDUZH, Shimla, 200 nulliparous women at term were divided into two groups based on inclusion and exclusion criteria. Pre - labor assessment of Bishop score was done. Group A received 400mg Mifepristone while group B was kept under expectant management. All women were reassessed after 48 hours. Result: 75 women in group A and 48 women in group B went into spontaneous labor within 48 hours (p=0.048).20 women in group A and 50 women in group B still had a Bishop score of < 6 which was statistically significant (p<0.001). Conclusion: Mifepristone is highly effective, safe, cheap, convenient and economical method for pre induction cervical ripening and induction of labor. Pre induction ripening of cervix further helps in increasing the rate of vaginal delivery and mifepristone can be considered as an attractive method of pre induction cervical ripening and labor induction.

Keywords: Mifepristone, cervical ripening, labor, induction

Edition: Volume 12 Issue 5, May 2023

Pages: 2172 - 2174

DOI: https://www.doi.org/10.21275/SR23523215711

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