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Review Papers | Pharmaceutical Science | India | Volume 12 Issue 6, June 2023 | Popularity: 5.2 / 10

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Method Development and Validation of Amoxicillin Trihydrate by HPTLC in Bulk and Pharmaceutical Dosage Form

Kalyan Kumar Yadav, Jyoti Verma

Abstract: Bacterial Infections are diseases that affect your skin, lungs, brain, blood, and other parts of the body. Common symptoms of bacterial infection include-Fever, Chills, Fatigue, Headache, etc can occur, Other symptoms include Redness of the skin, Ulcers, Diarrhoea, and Stomach pain produced by Bacteria, In such treatment Amoxicillin is the best therapeutic and efficacious treatment given in the last decades. Various method is used for the analytical separation of Amoxicillin by HPLC (High-Pressure Liquid Chromatography), and RP-HPLC (Revers Phase High-Pressure Liquid Chromatography) and provides good technical assistance, but current scenario the HPTLC method is used for the detection of many compounds. The HPTLC method is a powerful and accurate method for the detection of Amoxicillin Trihydrate, this method is very less costly and provides highly pr?cised results. By HPTLC various Validation parameters are produced like Specificity, Robustness, Ruggedness, linearity, Accuracy, Precision LOD (Limit of Detection) and LOQ (Limit of Quantification) is precisely obtained by the HPTLC method.

Keywords: HPTLC, HPLC, Amoxicillin Trihydrate, Validation, Antimicrobial

Edition: Volume 12 Issue 6, June 2023

Pages: 791 - 796

DOI: https://www.doi.org/10.21275/SR23602124321

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