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Analysis Study Research Paper | Emergency Medicine | India | Volume 12 Issue 6, June 2023 | Popularity: 5.2 / 10

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Assessing First Pass Success Rate with Low Dose Rocuronium during Rapid Sequence Intubation among Patients in an Emergency Department

Dr. Jerin Miriam Johnson, Dr. Jobin Jose Maprani, Dr. Yasir Sulaiman, Dr. Vaisakh R Vijay, Dr. Jeevan Jayakumar

Abstract: Introduction: Rapid sequence intubation is defined as the administration of a potent induction agent immediately followed by a rapidly acting paralytic agent to induce unconsciousness and motor paralysis to facilitate endotracheal intubation easier and safer. Rocuronium and its first - pass success rates were primarily researched in western populations. There have been very few studies on the topic among the Indian population. Therefore, it is crucial to perform studies to assess first pass success rate when a low dose rocuronium is combined with an induction agent in RSI in adult patients presenting to the emergency department such that it can be implicated in an anticipated difficult airway. Methods: A cross sectional study was conducted at the ED of Amala Institute of Medical Sciences over a period of 1.5 years. Associations between qualitative variables were tested using Fischer?s exact test and relation between qualitative and quantitative variables were tested using t test. P value <0.05 was assigned for statistical significance a priori. Results: In this study success rate of intubation in first attempt was tested using Fischer?s exact test when low dose rocuronium (0.3mg/kg) was administered which was found to be statistically significant with a p value <0.001. Other factors like age, gender and comorbidities were found to have no significance with administration of low dose rocuronium. Conclusion: This study shows that with low dose rocuronium a good first pass success rate could be obtained, thereby reducing complications associated with neuromuscular blocking agents. Although the co factors were of no significance when attributed with low dose rocuronium.

Keywords: Rapid sequence intubation, low dose rocuronium, first pass success

Edition: Volume 12 Issue 6, June 2023

Pages: 846 - 851

DOI: https://www.doi.org/10.21275/SR23606214619

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