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Case Studies | Dental Medicine | Indonesia | Volume 12 Issue 6, June 2023 | Rating: 5.2 / 10

Prevalence of Hypodontia in Down Syndrome (Scoping Review)

Stefani Magdalena Christanti | Risti Saptarini Primarti ^[3] | Willyanti Soewondo ^[2]

Abstract: Down syndrome caused by the extra chromosome on chromosome 21, hypodontia can occur in Down syndrome. The purpose of this study was to obtain the prevalence of hypodontia in Down syndrome from the literature study by using Scoping Review. The method follows the framework by Arksey and O'Malley. Study selection was carried out using Preferred Reporting Items for Systematic Review and Meta-analysis Scoping Review. Articles were searched using keywords, limit functions, inclusion criteria in search engines such as PubMed, EBSCOhost, and Google Scholar, as well as hand searching. There were total of 15 articles according inclusion criteria and analyzed. The prevalence of hypodontia in Down syndrome shows high variation among the studies. The lowest prevalence of hypodontia was 16.19% and the highest was 73.17%. Six studies showed that female had higher prevalence of hypodontia than male with a significant difference. Eleven studies provided description of which teeth, most frequently missing teeth after excluding the third molars were maxillary lateral incisors, mandibular lateral incisors, mandibular second premolars, and maxillary second premolars. This study shows that hypodontia is more common in individuals with Down syndrome than normal individuals, with a prevalence ranging from 16.19% to 73.17%.

Keywords: Down Syndrome, hypodontia, prevalence

Edition: Volume 12 Issue 6, June 2023,

Pages: 1507 - 1514