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Case Studies | Medicine | India | Volume 12 Issue 6, June 2023 | Rating: 5.1 / 10
Survival Case Report of Adult with Severe Amlodipine Intoxication
Nupur Pandya [3] | Shaurya Patel [2] | Kaushika Chaudhary [2] | Jyoti Vora
Abstract: Amlodipine is a commonly prescribed calcium channel blocker (CCB), overdose of which results in profound shock and pulmonary edema [1]. A 40 years old male with severe Amlodipine toxicity presented with hypotension and pulmonary edema to our Hospital. Patient management involved early and aggressive supportive measures, calcium infusion in large doses to overcome competitive blockade and Insulin therapy for positive inotropic effect. A rise in Blood pressure was noted in 3 days and insulin infusion was stopped and patient was discharged after 10 days with psychiatric consultation. Positive inotropic effect of insulin therapy in our patient supports previous finding of its use as first line therapy in management of CCB overdose.
Keywords: Amlodipine Toxicity, Calcium Channel Blocker, Insulin Infusion
Edition: Volume 12 Issue 6, June 2023,
Pages: 1567 - 1569