International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064




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Research Paper | Ophthalmology | India | Volume 12 Issue 7, July 2023 | Rating: 5.3 / 10


Utilizing Anterior Segment Optical Coherence Tomography for Comprehensive Analysis of Corneal Disorders

Dr. Manglesh Mohan Gupta | Dr. Bhalchandra S. Joshi | Dr. Vijay H. Karambelkar [2]


Abstract: Anterior segment optical coherence tomography (AS - OCT) is a form of OCT technology that has been adapted for clinical care and scientific research of ocular surface and anterior segment diseases present study aimed to assess the anterior segment optical coherence tomography in corneal disorders. Aim: Study of anterior segment optical coherence tomography in corneal disorders. Material & method: This single centre hospital based prospective study, conducted in patients who attended ophthalmology outpatient department and undergoing treatment in our institute over a period of 18 months from November 2020 to May 2022. Patients with corneal disorder willing to be part of study were included and patients not compliant were excluded from the study. Non - invasive, non - contact diagnostic method that uses infrared light to analyse the cornea. The collected data were analysed using SPSS v21 operating on windows 10 with appropriate analytical testing with significance of p<0.05 was considered. Results: In present study total of 90 patients fulfilling inclusion criteria were included after obtaining the informed consent. The mean age of patients was 52.09?13.70yrs of age. Among the study participants, 64.4% were male patients and 35.6%were female patients, with male preponderance. Among the study participants, 52.2% were with right eye involvement, 36.7% with left eye involvement and 11.1% with bilateral involvement. Among the study participants, 26.66% had corneal opacity, 30.00% had corneal infection which showed the maximum distribution among the diseases taken in account. Quantitative analysis of central corneal thickness, oedema thickness and infiltrate thickness were assessed in different corneal pathologies. Corneal hyper - reflectivity is an increase in whiteness, whereas the definition of corneal hypo - reflectivity is an increase in darkness. In case of scars, oedema, fibrosis, or material deposits on the cornea, there may be variable increase in reflectivity. Hyper - reflective band under the corneal epithelium is visible on corneal AS - OCT imaging in patients who have a clinical history of inflammation and corneal thinning. Conclusion: Study found a significant findings and utility of quantitative and qualitative analysis of corneal pathology by AS OCT in evaluation and treatment of corneal disorder.


Keywords: Anterior Segment Optical Coherence Tomography, Corneal Disorders, quantitative analysis, qualitative analysis, clinical study


Edition: Volume 12 Issue 7, July 2023,


Pages: 2265 - 2268


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