International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


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Research Paper | Medicinal Plants | Vietnam | Volume 12 Issue 8, August 2023 | Popularity: 4.5 / 10


     

Comprehensive Analysis of Hedera Helix Leaves: Chemical Composition and its Antibacterial and Antidiabetic Potentials

Dinh Luu Nhat Quynh, Tran Chieu An, Doan Le Quynh Nhu, Tran Phan Huynh Nhu, Pham Hong Ngoc, Phung Van Trung


Abstract: This research aimed to study on chemical constituents and investigate bioactivities of Hedera helix, including antibacterial and antidiabetic. From the methanol extract of H. helix leaves collected in Da Lat province (Vietnam), four triterpene saponins were isolated and determined as ?-hederin (1), hederacoside D (2), hederacoside B (3), and hederacoside C (4). Their chemical structures were elucidated by NMR. The fractions and isolated compounds of H. helix leaves showed low antibacterial activity against gram-positive (Staphylococcus aureus) and gram-negative (Pseudomonas aeruginosa) bacteria. In addition, these samples were found to have low?-glucosidase inhibitory activity at tested concentration.


Keywords: Hedera helix, Staphylococcus aureus, Pseudomonas aeruginosa, ?-glucosidase, triterpene saponins


Edition: Volume 12 Issue 8, August 2023


Pages: 467 - 472


DOI: https://www.doi.org/10.21275/SR23727195358



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Dinh Luu Nhat Quynh, Tran Chieu An, Doan Le Quynh Nhu, Tran Phan Huynh Nhu, Pham Hong Ngoc, Phung Van Trung, "Comprehensive Analysis of Hedera Helix Leaves: Chemical Composition and its Antibacterial and Antidiabetic Potentials", International Journal of Science and Research (IJSR), Volume 12 Issue 8, August 2023, pp. 467-472, https://www.ijsr.net/getabstract.php?paperid=SR23727195358, DOI: https://www.doi.org/10.21275/SR23727195358

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