International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064




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Analysis Study Research Paper | Anaesthesiology | India | Volume 12 Issue 8, August 2023 | Rating: 5.2 / 10


Magnesium Sulphate as an Effective Adjuvant for Postoperative Pain Management in Lower Limb Orthopaedic Surgeries

Dr. Jinal Subhash Tanna | Dr Janam Yatin Merchant


Abstract: Objective: To observe the total analgesic requirement in the first 24 hrs of the postoperative period, if there is any prolongation of the time to rescue analgesia and incidence of complications in patients given Magnesium sulphate and the control group. Methods: The study comprised 50 patients undergoing lower limb orthopaedic surgery who were ASAGrade I & II and were between the age of 20 and 65. After receiving spinal anaesthesia, 25 of these patients (Group A) got Magnesium Sulphate at a dose of 50 mg/kg in 100 ml bottles of normal saline, while the other 25 patients (Group B) received only NS (Group B). It was recorded when the first dose of analgesia was needed. Patients were watched for signs of sedation, hypotension, shivering, nausea, vomiting and pruritus. The total amount of analgesics needed in the first 24 hours following the operation was noted. Results: In Group A and Group B, the mean ? SD of the time to rescue analgesia was 444? 130 minutes and 287? 55 minutes, respectively. The total analgesic requirement of Group A was significantly less as compared to Group B in the first 24 hours of the surgery. Incidence of complications were not significantly higher in the study group. Conclusion: We come to the conclusion that patients receiving spinal anaesthesia for lower limb orthopaedic procedures can safely receive IV magnesium sulphate in a bolus dose of 50 mg/kg to reduce initial postoperative pain with a minimal incidence of complications.


Keywords: Magnesium Sulphate, Postoperative Pain Management, Lower Limb Orthopaedic Surgeries, Spinal Anaesthesia, Analgesic Requirement


Edition: Volume 12 Issue 8, August 2023,


Pages: 97 - 104



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