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Research Paper | Biochemistry | India | Volume 12 Issue 8, August 2023 | Rating: 5.2 / 10

Analysis of Standard Biochemical Parameters in Mycobacterium Tuberculosis - Infected Patients in the Doda Region of India

Azhar Saleem Zargar

Abstract: Background: This experimental work was performed to analyze the effect of TB in patients suffering from the ailment. This constituent study was carried out in the Doda region of India. This study aims to correlate the conventional biochemical serum markers with tuberculosis infection. Method: The study was performed on a total of 240study participants, consisting of 120TB cases and 120 controls. TB patients' mean age (SD) was 45.53?10.27years and healthy controls were39.09?11.58 years. The assay of the study was to evaluate the concentration of serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), Zinc, CRP, and ESR levels in TB patients of the Doda region, attending OPD and Medicine department of Government medical college Doda, J&K UT. Result: The results revealed an increase in crucial biochemical enzymes and inflammation markers of the liver i. e. SGOT (40%), SGPT (34%), ESR (71%), and CRP (78%) levels in patients with tuberculosis compared to health groups. Furthermore, the result also documented a decrease in Zinc (53%), levels in patients suffering from tuberculosis compared to healthy groups. Conclusion: Our results concluded that there was a decrease in Zn2+ levels, and an increase in the levels of SGOT, SGPT, ESR & CRP in MTB patients with pulmonary tuberculosis compared to the control group, which is an indication of inflammation of, and liver damage among MTB patients.

Keywords: TB, SGOT, SGPT, CRP and ESR

Edition: Volume 12 Issue 8, August 2023,

Pages: 2261 - 2264