Downloads: 2 | Views: 90 | Weekly Hits: ⮙2 | Monthly Hits: ⮙2

Research Paper | Paediatrics | India | Volume 13 Issue 10, October 2024 | Popularity: 5.4 / 10

Rate This Article!      

Clinical Profile, Precipitating Factors, and Outcome of Diabetic Keto Acidosis in Type 1 Diabetes Mellitus Between 1 to 15 Years

Dr. Abdul Razak Bidari, Dr. Sudhir D, Dr. Shivani Nag, Dr. Anil

Abstract: Background: Diabetic ketoacidosis (DKA) is a life - threatening complication of Type 1 diabetes, particularly in paediatric patients. This study is aimed to analyse the clinical profile, precipitating factors, and outcomes of DKA in children aged 1 to 15 years, with a focus on identifying key factors that influence patient outcomes. Methods: A descriptive, observational study, conducted at a tertiary care hospital, including 50 children diagnosed with Type 1 diabetes and admitted with DKA. Data were retrospectively collected on demographic characteristics, clinical symptoms, blood pressure levels, ketone bodies, insulin compliance, injection techniques, and patient outcomes. Descriptive statistics were used to analyze the data. Results: The study population had a mean age of 10.81 years, with a majority being females (70%). Clinical symptoms such as polyuria, polydipsia, vomiting, and hurried breathing were prevalent in over 90% of cases. Hypertension was observed in 28% of patients. A significant majority (80%) had 3+ ketone bodies in both serum and urine. Insulin compliance was poor in 34% of the patients, with 56% using correct injection techniques. The mortality rate was 10%, while 90% of the patients showed improvement. Vital statistics revealed elevated heart and respiratory rates, with mean glucose levels at 553.44 mg/dL and mean pH at 6.8576, indicating severe acidosis. Conclusions: The study highlights the critical nature of DKA in children with Type 1 diabetes, emphasizing the need for early detection, effective management, and ongoing patient education to improve treatment adherence. Despite the majority of patients responding well to treatment, the mortality rate underscores the importance of timely intervention. Future research should focus on larger, multi - center studies to further explore strategies for preventing DKA and improving patient outcomes.

Keywords: Diabetic Ketoacidosis, Type 1 Diabetes, Paediatric, Insulin Compliance, Clinical Outcomes

Edition: Volume 13 Issue 10, October 2024

Pages: 391 - 396

DOI: https://www.doi.org/10.21275/SR241002163613

Make Sure to Disable the Pop-Up Blocker of Web Browser

Click to Cite this Article