Downloads: 2 | Views: 68 | Weekly Hits: ⮙1 | Monthly Hits: ⮙2
Analysis Study Research Paper | Anaesthesiology | India | Volume 13 Issue 10, October 2024 | Popularity: 5 / 10
Efficacy of Intravenous Tramadol vs Paracetamol Infusion for Postoperative Pain in Patients Undergoing Laparoscopic Surgery: A Single - Blinded Randomised Comparative Study
Gajendra Singh, Rajesh Kumar, Pramod Kumar, Sapna Bansal
Abstract: Aim: To compare the postoperative analgesic efficacy of IV paracetamol and IV tramadol in patients undergoing laparoscopic surgery. Study Design: Prospective, Single Blinded, Randomised Comparative. Setting: Operating Room, Post Operative Room and Surgery Ward of a University Hospital. Patients: 100 ASA physical status I and II patients of age 20 - 60 scheduled for laparoscopic surgeries were included. Interventions: Subjects were premedicated with oral Ranitidine 150mg and Alprazolam 0.25mg/kg 1 night prior to the surgery and patient was kept nil per oral. Patients were randomized in two groups after inducing anesthesia. The Paracetamol (P) group (n= 50) received 20 mg/kg of IV paracetamol and tramadol (T) group (n=50) received 2mg/kg of IV tramadol. All patients received first dose of study drug at the end of surgery during skin suturing. Measurements: Hemodynamic parameters like Heart Rate, Blood Pressure, Oxygen Saturation and pain score using VAS scale were recorded at baseline, 15 minutes, 30 minutes, 1 hour, 3 hour and 6 hours. Frequency of Xerostomia, Nausea and emesis was noted. Any rescue analgesia required was noted. Results: No clinical or statistical association with demographic parameters between the groups was observed. No statistical significance was found in post operative pain scores in both the groups. During postoperative follow - up intervals, paracetamol showed significantly lower VAS scores as compared to tramadol at baseline, 15 min, 30 min, 1 hour, 3 hour and 6 hours follow up intervals.10 patients in tramadol group had nausea postoperatively (p>0.05). No side effect attributable to paracetamol was noticed. Conclusion: IV Paracetamol can be advocated as an efficacious, safer and pharmacoeconomic analgesic drug for post - operative pain relief in comparison to IV tramadol in Indian Population.
Keywords: Post Operative Analgesia, Tramadol, Paracetamol, Laparoscopic Surgery
Edition: Volume 13 Issue 10, October 2024
Pages: 709 - 715
Make Sure to Disable the Pop-Up Blocker of Web Browser