International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064


Downloads: 1 | Views: 53 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Research Paper | Obstetrics and Gynecology | India | Volume 13 Issue 10, October 2024 | Popularity: 4.9 / 10


     

Efficacy and Safety of Oral Mifepristone as a Cervical Ripening Agent for Labor Induction in Low-Risk Full-Term Live Pregnancies Beyond 40 Weeks of Gestation: A Randomized Controlled Study

Dr. Nikita Yadav, Dr. Hanslata Gehlot, Dr. Rakesh Bagri


Abstract: This study evaluates the efficacy and safety of oral mifepristone as a cervical ripening agent for inducing labor in low-risk, full-term live pregnancies beyond 40 weeks of gestation. In this randomized controlled trial, 100 pregnant women were equally divided into two groups: the study group receiving 200 mg oral mifepristone and the control group undergoing expectant management. The primary outcomes measured were improvement in Bishop's score within 24-48 hours and the onset of labor within 72 hours. Secondary outcomes included allocation-to-delivery interval, the requirement for additional labor inducers, maternal and neonatal outcomes, and mode of delivery. Results showed significant improvements in cervical ripening, reduced need for additional labor inducers, and a shorter induction-to-delivery interval in the mifepristone group. Mifepristone demonstrated excellent safety and efficacy in inducing labor with minimal side effects, suggesting its potential role as a primary agent in labor induction protocols.


Keywords: Mifepristone, Cervical ripening, Term pregnancy, Labor induction, Pregnancy outcomes


Edition: Volume 13 Issue 10, October 2024


Pages: 965 - 968



Make Sure to Disable the Pop-Up Blocker of Web Browser




Text copied to Clipboard!

Similar Articles

Downloads: 0

Masters Thesis, Obstetrics and Gynecology, India, Volume 11 Issue 2, February 2022

Pages: 1246 - 1248

A Comparative Study of Intracervical Foley's Catheter with Oxytocin and without Oxytocin in Inducing Labour in Women with Unfavourable Cervix for Reducing Induction Delivery Interval

Dr. Jothisundaram, Dr. A. Manimegalai

Share this Article

Downloads: 0

Analysis Study Research Paper, Obstetrics and Gynecology, India, Volume 11 Issue 11, November 2022

Pages: 704 - 710

Mifepristone and Misoprostol Compared with Misoprostol alone for Delivery after Fetal Death between 14 and 28 Weeks of Gestation

Dr. J. Rishitha Priyanka, Dr. Kalpana

Share this Article

Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Comparative Studies, Obstetrics and Gynecology, India, Volume 10 Issue 6, June 2021

Pages: 1537 - 1541

Comparative Study of Efficacy and Safety of Mifepristone and Foley's Catheter in Induction of Labour

Amrutha .A .V, Shaila C, Ravi Karad

Share this Article

Downloads: 1

Comparative Studies, Obstetrics and Gynecology, India, Volume 10 Issue 7, July 2021

Pages: 507 - 512

To Compare the Effect of Inducing Agents Dinoprostone Sustained Release Vaginal Pessary and Intracervical Gel on Labour and its Fetomaternal Outcome

Ashima Taneja, Pooja Tandon, Mehtab Kaur, Manpreet Kaur, Gagandeep Kaur, Muskan Chaudhary, Gurpinder Dhillon, Aashna Rao, Mayur Goyal, Parampratap Singh

Share this Article

Downloads: 1

Comparative Studies, Obstetrics and Gynecology, India, Volume 10 Issue 9, September 2021

Pages: 135 - 138

A Comparative Study of Intracervical Foley's Catheter Instillation Vs Intracervical Dinoprostone Gel for Pre - Induction Cervical Ripening

Dr. Priyanka Gahlout, Dr. Renu Rohatgi, Dr. Tabassum Ahmed, Dr. Sangeeta Kumari

Share this Article
Top