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Case Studies | Otorhinolaryngology | Malaysia | Volume 13 Issue 1, January 2024 | Rating: 4.3 / 10
A Comprehensive Case Study on Extranodal NK/T - Cell Lymphoma, Nasal Type: Clinical Insights and Challenges
Loong Jie Jun | Priyanka Menon
Abstract: Extranodal NK/T - cell Lymphoma of nasal type is a rare and highly aggressive subtype of non - Hodgkin lymphoma, closely associated with the Epstein - Barr virus. It exhibits a poor prognosis and limited responsiveness to available treatments irrespective of clinical stage and therapy. We report a case of a 54 years old gentleman who presented to the hospital after being unwell for one week. Histology study revealed lymphoma cells which are polymorphous, admixed with small lymphocytes, angiocentric growth invasion and positive immunohistochemistry for CD2, CD 56, cytoplasmic CD3+, surface CD3?ve. Patient was referred for further treatment however, died while ongoing treatment. This case study adds valuable insights into the clinical presentation, diagnosis, and challenges in managing Extranodal NKT - Cell Lymphoma, emphasizing the need for increased awareness and research in this area.
Keywords: Extranodal NK/T - cell lymphoma, nasal type, non - Hodgkin lymphoma, Epstein - Barr Virus Infections
Edition: Volume 13 Issue 1, January 2024,
Pages: 925 - 927