Downloads: 2 | Views: 51 | Weekly Hits: ⮙2 | Monthly Hits: ⮙2

Comparative Studies | Anaesthesiology | India | Volume 13 Issue 12, December 2024 | Popularity: 5.3 / 10

Rate This Article!      

A Comparative Clinical Study of Two Different Doses of Dexmedetomidine Mixed as Adjuvant to Levobupivacaine 0.5% Solution for Giving Supra-Clavicular Brachial Plexus Block, in Patients Undergoing Upper Limb Surgeries

Dr. Vaibhav Singh, Dr. Shobhit Singh, Dr. Prateek Agarwal, Dr. P. S. Malviya

Abstract: Background and Aims: Many studies have been conducted using dexmedetomidine as adjuvant to local anaesthetics in peripheral nerve blocks, but few studies compare the effect of different doses of dexmedetomidine. We aimed at comparing the clinical profile of different doses of dexmedetomidine as adjuvant to levobupivacaine in supraclavicular brachial plexus block and finding out the dose which provides maximum improvement in block parameters with minimum undesirable effects. Methods: After obtaining institutional ethical committee approval the study was started. 90 patients belonging to ASA I and II, undergoing elective upper limb surgery were randomly allocated into three groups of 30 each. Ultrasound guided Supraclavicular brachial plexus blocks were performed in each group. Group LC received plain levobupivacaine 0.5%, group LD50 and LD100 received 50mcg and 100mcg dexmedetomidine along with levobupivacaine 0.5% (100mg) respectively. Onset, duration of sensorimotor block, hemodynamic stability and adverse effects were assessed throughout the duration of surgery. Result: LD100 group showed statistically significant decrease in onset time and increase in duration of sensory and motor blockade compared to LD50 group and LC group (P = 0.001). We observed a decrease in mean heart rate with an increasing dose of dexmedetomidine. Incidence of bradycardia and mean sedation scores were more with group LD 100 than group LD 50 and LC. Conclusion: We conclude that dexmedetomidine when used in a dose of 50?g as adjuvant in peripheral nerve block, has the advantages of conscious sedation and hemodynamic stability in addition to significant improvement in block characteristics.

Keywords: Dexmedetomidine, Ultrasound guided, Supraclavicular brachial plexus, Levobupivacaine 0.5%

Edition: Volume 13 Issue 12, December 2024

Pages: 418 - 421

DOI: https://www.doi.org/10.21275/SR241203222409

Make Sure to Disable the Pop-Up Blocker of Web Browser

Click to Cite this Article

Similar Articles