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Case Studies | Pathology | India | Volume 13 Issue 12, December 2024 | Popularity: 5.6 / 10

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Primary Renal Synovial Sarcoma and RCC with Sarcomatoid Differentiation: A Case Series of Rare Occurrences

Dr. Divya Sharma, Dr. Swati Agarwal

Abstract: Primary renal synovial sarcoma and Renal cell carcinoma (RCC) with sarcomatoid differentiation are rare renal tumors comprising only 1% and 4% of all renal tumours respectively. Both of which are highly aggressive variants. These tend to metastasise early and carry poor prognosis with short survival of patient. Primary renal synovial sarcoma harbours characteristic translocation t (X; 18) (p11; q11) whereas RCC with sarcomatoid originates from epithelial - mesenchymal transition (EMT) therefore contains both epithelial (carcinoma) and mesenchymal (sarcomatoid) features. Both the tumors lack any specific imaging or clinical findings thus require specific pathological tests for correct diagnosis and early detection for better outcome of patient. One case report of each tumor is presented.

Keywords: Primary Renal Synovial Sarcoma, Renal cell carcinoma with sarcomatoid differentiation, Renal cell carcinoma

Edition: Volume 13 Issue 12, December 2024

Pages: 914 - 917

DOI: https://www.doi.org/10.21275/SR241210130305

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