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Review Papers | Medicine | India | Volume 13 Issue 2, February 2024 | Popularity: 6 / 10

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A Systematic Review of Peak Expiratory Flow Rate (PEFR) Values in Pre and Post Nebulization with Two Different Techniques in Adult Asthmatic Patients

Sreekanth Komath Mohan, Shashidhar Kotian M, Udayakumar Rao, Namitha R, Suhair PP, Hasib Ali

Abstract: Peak Expiratory Flow Rate (PEFR) is the primary outcome metric in this review of the relative efficacy of masks and mouthpiece nebulization in the treatment of asthma. Following a comprehensive search of numerous databases, which include Scopus, CINAHL, PubMed, EMBASE, and the Cochrane Central Register of Controlled Studies (CENTRAL), eight randomised managed studies were observed that fulfilled the inclusion standards. The research that had been chosen had been published during the past 5 years and covered a huge variety of those who had asthma, whether it became mild persistent bronchial asthma, uncontrolled allergies, or extreme exacerbations. The suggested PEFR improvement after mouthpiece nebulization changed from 18% to 31%, with the majority of studies locating enhancements of 20?30%. In contrast, mask nebulization revealed a relatively decreased mean percentage PEFR upgrade of 12?21%. Inspiring troubles approximately the viable advantages of mouthpiece nebulization versus mask processes were raised through the observed discrepancies. Study variability is due in part to the fact that researchers checked out variables impacting response, inclusive of the severity of asthma, the sort of medication used, the duration of remedy, the degree to which respondents adhered to the approach, their baseline lung function, and the presence of any co-morbidities. The Cochrane Risk of Bias evaluation verified the need for rigorous methods for future studies. Significant therapeutic implications for acute asthma exacerbations and regular care come from the consequences, which show that mouthpiece nebulizers may offer truly large PEFR enhancements. For those who are sensitive to masks, mouthpiece nebulization continues to be an option to remember. Scores for asthma manipulation, quality of life, adverse results, and healthcare use are other consequences that must be the point of interest of the destiny examination in addition to PEFR. Larger meta-analyses are necessary to corroborate those early consequences and provide useful evidence-based decision-making in adult asthma management.

Keywords: Peak Expiratory Flow Rate (PEFR), Mask Nebulization and Mouthpiece Nebulization

Edition: Volume 13 Issue 2, February 2024

Pages: 1245 - 1252

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