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Experimental Result Paper | Toxicology Science | India | Volume 12 Issue 3, March 2023 | Rating: 5 / 10

Assessment of the Effect of Melamine on Some Biochemical Parameters in Adult Albino Rat

Mukti Mondal | Pinaki Samanta | Satinath Singha | Nibedita Mondal

Abstract: Melamine is an organic compound with the formula is C3H6N6. Melamine is sometimes legally added to food product in order to increase the apparent protein content. The adverse effect of melamine on some animal model has been reported but the effects of melamine on biochemical parameters have not been reported. So, in this study we report here the adverse effect of melamine on some biochemical parameters in rat model. The dosages of melamine selected according to the LD50. There are two experimental groups for 28 days exposure duration. We observed from our experimental study that melamine increases the level of total protein, SGOT and SGPT and no significant alteration of serum ALP level were observed compared to control. Histologically, melamine causes significant degenerative alteration in the wall structure of heart and liver. From this study, it may be concluded that melamine produces hazardous adverse effect in different blood parameters.

Keywords: Melamine, Serum glutamic oxaloacetic transaminase, Serum glutamate pyruvate transaminase, Alkaline phosphatase, Rat

Edition: Volume 12 Issue 3, March 2023,

Pages: 1816 - 1819