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Research Paper | Medical Science | Indonesia | Volume 13 Issue 3, March 2024 | Popularity: 5.8 / 10

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Description of Viral Load in HIV Patients Receiving ARVS in Klungkung Regency Hospital

I Gusti Agung Wedanta Mahadewi, Ni Made Putri Purnama Dewi

Abstract: Human immunodeficiency virus (HIV) is a viral infection that attacks the body's immune system. Meanwhile, acquired immunodeficiency syndrome (AIDS) is the highest stage of this infection. HIV targets white blood cells, which weaken the body's immune system. Viral load and CD4 counts are markers used to see the response to ARV therapy and disease progression in HIV patients. Viral load examination can be used to detect earlier and more accurately in patients who experience treatment failure compared to using immunological or clinical criteria. Viral load examination can also be used to determine the level of viral replication and as data to decide on changing therapy from first line to second line therapy so clinical outcomes can be better. The design of this study is a descriptive observational. The sample in this study was 155 patients at Klungkung Regional Hospital who were diagnosed with HIV/AIDS and had been undergoing treatment for >6 months. From the study, data was obtained from 155 samples, 143 (92.3%) respondents had suppressed viral loads and 12 (7.7%) respondents were not suppressed. This result cannot be separated from the benefits of using ARVs as early as possible. And these results are in accordance with the HIV Prevention Trial Network Study, state that ARV therapy is the most effective prevention of HIV transmission at this time, so that early administration of ARVs can reduce HIV transmission by 93% in non - HIV sexual partners (serodiscordant couples).

Keywords: HIV, AIDS, viral load, CD4 counts, ARV therapy

Edition: Volume 13 Issue 3, March 2024

Pages: 1199 - 1202

DOI: https://www.doi.org/10.21275/SR24318104925

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