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Research Paper | Neurology | Cambodia | Volume 13 Issue 6, June 2024 | Rating: 4.4 / 10
Common Clinical Presentations of and the Prevalence of Epilepsy in Adult Patients with Neurocysticercosis
Navuddh Oam [4] | Kimsour Seng | Kimeach Kong [3] | Samith Sourn [3] | Navuth Chum [3]
Abstract: Cysticercosis is the most common parasitic disease of the nervous system in humans and the single most common cause of acquired epileptic seizures in the developing countries, where prevalence rates of active epilepsy are twice those in developed countries. In Cambodia, neurocysticercosis played an important role as parasitic disease of the nervous system and the common cause of seizure disorders.This study aimed to study of common clinical presentations of neurocysticercosis in hospitalized patients and to investigate the prevalence of epilepsy in patients with neurocysticercosis. This was retrospective cohort study that involved 56 adults subjects diagnosed with neurocysticercosis (NCC) presented at Department of Neurology, Khmer-Soviet Friendship Hospital, between 2015 to 2020. All data were stored and analyzed by using SPSS version 20 and data entry was carried out with coding and verification. The qualitative and quantitative data were expressed as the mean with standard deviation (SD), or median (IQR) and as the number of observation with percentage (%), respectively. Both dependent and independent variables used a nominal measurement scale. There were 56 subjects included in our study, 67.8% were male, and 32.2% were female. The prevalence of epilepsy was 57.1%; the median age 53 years (IQR 40-63 years. Headache and seizure were the common chief complains for neurocysticercosis patients, 66.1% and 57.1%, respectively, motor weakness 28.5% and impaired consciousness 17.8%. During the hospital stay headache was the major symptom among the subjects, 75.0%). The following symptoms were seizure (39.2%), motor deficit (26.7%), nausea/vomiting (14.2%), cognitive decline (12.5%), vertigo and fever were the less common symptoms. This concluded that the definitions of manifestations were very rarely provided, and varied from study to study, the proportion of NCC cases with seizures/epilepsy and the proportion of headaches were consistent across studies. NCC might still have a relevant presence in Cambodia and might play an important role as a cause of acquired epilepsy.
Keywords: neurocysticercosis, epilepsy, clinical manifestations, prevalence
Edition: Volume 13 Issue 6, June 2024,
Pages: 691 - 693