Downloads: 3 | Views: 18 | Weekly Hits: ⮙4 | Monthly Hits: ⮙4
Case Studies | Pediatrics | India | Volume 13 Issue 7, July 2024 | Rating: 4.3 / 10
Multi-System Inflammatory Syndrome in Children: Varied Presentations and Implications in the Context of COVID-19
Jayakrishnan VY | Ashish K Simalti | Athul N Gopinath
Abstract: We present a case of a 5 ?-year-old boy initially admitted with high-grade continuous fever, vomiting, and loose stools for two days. Despite empirical treatment with intravenous broad-spectrum antibiotic administration, the fever persisted. On Day 6, he developed bilateral non-purulent conjunctival congestion, facial puffiness, and tachycardia. Subsequent diagnosis revealed Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19, confirmed by positive COVID-19 IgG antibodies in both the child and mother. Laboratory investigations revealed elevated Troponin-T and N-terminal pro-B-type natriuretic peptide (NT-pro BNP), indicating cardiac involvement. Treatment with intravenous immunoglobulin (IVIG), Methylprednisolone, and Aspirin led to immediate fever subsidence and improvement in blood pressure. Despite transient bradycardia lasting for 48 hours, the child showed significant clinical improvement and was discharged after stabilization. This case was managed in a peripheral resource-limited setting, underscoring the varied presentations of MIS-C and highlighting the importance of early recognition and management in improving patient outcomes.
Keywords: Multisystem inflammatory syndrome in children, sars-cov-2, MIS-C, COVID-19
Edition: Volume 13 Issue 7, July 2024,
Pages: 770 - 772