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Research Paper | Anaesthesiology | India | Volume 13 Issue 7, July 2024 | Rating: 3.7 / 10
A Comparison between Ringer?s Lactate (RL) Solution and 6% Hydroxy Ethyl Starch (HES) in the Prevention of Hypotension in Patients Undergoing Cesarean Section under Spinal Anaesthesia
Dr. Mofizul Hoque | Dr. Karuna Kumar Das [2] | Dr. Monjit Shyam
Abstract: Background: Arterial hypotension is the leading cause for maternal mortality and morbidity following spinal anesthesia in parturients undergoing cesarean section. Active management of hypotension following spinal anaesthesia and its prevention is vital for patient?s safety. Preloading with either colloid or crystalloid prevents the severity of hypotension following spinal anaesthesia. Objectives of our study was to compare the efficacy of Ringers lactate solution preloading (1000 ml) and 6% hydroxyl ethyl starch preloading (500 ml) in the prevention of hypotension following spinal anesthesia in caesarean section. 1 Materials and methods: 150 parturients of age between 18 - 40 years and of ASA physical status II who were posted for cesarean section under spinal anaesthesia was taken for the study. The patients were randomly allocated into 2 equal groups. Group A received 500 ml of 6% hydroxyl ethyl starch (HES) and group B received 1000 ml of ringer?s lactate (RL) solution just prior to administration of spinal anaesthesia. The incidence of hypotension in two groups were compared. Mean systolic blood pressure, mean diastolic blood pressure, mean arterial blood pressure, vasopressor requirement and mean heart rate were measured in both the groups. Results: Incidence of hypotension was significantly more in ringer lactate group. Vasopressor requirement was also low in hydroxyl ethyl starch group compared to ringer lactate group. Conclusions: Preloading patients with 6% hydroxyl ethyl starch (HES) is better than preloading with lactated ringer?s solution as it produces better hemodynamic stability to subjects.
Keywords: Hypotension, Hydroxyl ethyl starch, Ringer?s lactate, Mean arterial pressure
Edition: Volume 13 Issue 7, July 2024,
Pages: 1109 - 1111