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Research Paper | Pharmaceutical Science | India | Volume 13 Issue 8, August 2024 | Popularity: 5.2 / 10

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Method Development and Validation of Pinaveriumbromide in Bulk form by UV - Visible Spectroscopy

A. Shailaja, P. Aliveni, M. Saseendra, Aishwarya

Abstract: The aim of this work was to develop and validate a simple estimation of Pinaverium bromide in bulk by using UV spectroscopic method. The method was developed using n - butyl alcohol as the solvent and absorbance was observed at 285nm. Beers law was obeyed the concentration ranges from 10 - 50?g/ml. Calibration curve shows a linear relationship between the absorbance and concentration. The line equation Y=0.0888x+0.033 with correlation coefficient (r) of 0.9999 was obtained. The method was validated as per ICH guidelines. The method was validated statistically and by recovery studies. The percentage recovery was found to be in the range of 98%. The %RSD value was found to be less than 2.

Keywords: Pinaverium Bromide, UVvisible spectroscopy, method validation, pharmaceutical analysis, nbutyl alcohol

Edition: Volume 13 Issue 8, August 2024

Pages: 1383 - 1387

DOI: https://www.doi.org/10.21275/SR24822115203

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