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Narrative Review | Pathology | India | Volume 13 Issue 9, September 2024 | Popularity: 6.3 / 10

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Primary Small Cell Carcinoma of Urinary Bladder with Review of Literature

Dr. Aroma Daultani, Dr. Alpana Jain, Dr. Alka Mittal

Abstract: Small cell carcinoma of the urinary bladder is a rare disease. It shares similarities in age of presentation, sex preference, symptoms, and appearance with conventional urothelial carcinoma. However, it is significantly more aggressive in its biological behaviour even when compared at similar stages. Metastasis is common at the time of diagnosis and prognosis is poor. Histologically, it resembles small cell carcinomas found in the lungs and other organs, though it exhibits lower reactivity to typical neuroendocrine markers. This cancer presents significant diagnostic challenges as its clinical presentation mimics other bladder tumours. We present an interesting and uncommon case, initially misdiagnosed as transitional cell carcinoma in the transurethral resection specimen. This case report presents a rare instance of Small cell carcinoma of the urinary bladder in a 56 - year - old male, shedding light on the diagnostic journey. The patient presented to the urological department with haematuria, dysuria, and hypogastric pain. Initial investigations revealed a bladder mass. A computed tomography (CT) scan was used to evaluate local and distal extension. A comprehensive histopathological examination, including immunohistochemistry, confirmed Small cell carcinoma of the urinary bladder.

Keywords: Small cell carcinoma, Urinary bladder, neuroendocrine tumor

Edition: Volume 13 Issue 9, September 2024

Pages: 1429 - 1433

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