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Review Papers | Medical Science | India | Volume 13 Issue 10, October 2024 | Popularity: 4.6 / 10

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Equations to Calculate Estimated Glomerular Filtration Rate (eGFR)

Dr. R. Dhananjayan

Abstract: Chronic kidney disease (CKD) is defined by the presence of kidney damage or decreased kidney function for at least three months, irrespective of the cause. The majority of patients with CKD are at risk of accelerated cardiovascular disease and death. The major challenge in preventing kidney disease relates to the early identification of high risk patients. The role of the clinical laboratory to screen, detect, manage and follow CKD is very important. Two variables are of particular interest in this context: glomerular filtration rate (GFR) and albuminuria or proteinuria. According to these two parameters, a diagnosis of CKD will be made and important decisions will be taken regarding therapy. The GFR is generally estimated from serum concentrations of endogenous filtration markers such as creatinine or cystatin C. During the past two decades, automated clinical laboratory reporting of GFR estimated using creatinine (eGFRcr) has become widespread, coincident with increased awareness of CKD. This paper focuses on various equations to calculate estimated GFR (eGFR) in clinical practice based on the serum concentration of endogenous biomarkers and demographic data.

Keywords: CKD, eGFR, Creatinine, Cockcroft and Gault, MDRD, CKD - EPI

Edition: Volume 13 Issue 10, October 2024

Pages: 263 - 264

DOI: https://www.doi.org/10.21275/SR24925115310

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