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Experimental Result Paper | Chemistry | India | Volume 14 Issue 2, February 2025 | Popularity: 5.2 / 10
Synthesis, Characterization, and Anti-Mycobacterial Evaluation of Oxadiazole and Pyrazolone Derivatives
Vijay J. Desale, Ramesh S. Yamgar
Abstract: Hydrazides and hydrazones are important precursors for synthesizing heterocyclic compounds. This study focuses on the synthesis and characterization of pyrazolone and 1,3,4-oxadiazole derivatives using spectroscopic techniques. These compounds were screened for their anti-mycobacterial activity, showing promising results. Additionally, in silico ADMET predictions were performed to evaluate their chemical properties. The results indicate the potential of these derivatives as effective anti-tuberculosis agents, paving the way for further biological evaluations.
Keywords: Hydrazide, hydrazone, oxadiazole, pyrazolone, anti-tuberculosis
Edition: Volume 14 Issue 2, February 2025
Pages: 1241 - 1244
DOI: https://www.doi.org/10.21275/SR25219221505
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