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Research Paper | Medicine | India | Volume 14 Issue 2, February 2025 | Popularity: 5.4 / 10
A Study of the Serum Magnesium Levels in St-Elevation Myocardial Infarction and its Correlation to Arrhythmia in Patients Admitted in a Tertiary Care Hospital of South Gujarat
Dr. Maulik Sakhavala, Dr. Prafful Kothari, Dr. Sanya Nishal, Dr. Saakshi Kothari
Abstract: Background: Cardiovascular diseases remain one of the leading causes of morbidity and mortality worldwide, with ST-Elevation Myocardial Infarction (STEMI) representing a significant and life-threatening manifestation of ischemic heart disease. STEMI occurs when there is a complete blockage of one of the coronary arteries, leading to severe damage to the heart muscle. Despite advances in diagnostic and therapeutic techniques, the prognosis for STEMI patients continues to depend on a variety of factors, including the occurrence of complications such as arrhythmias. Aims & Objectives: To investigate the relationship between serum magnesium levels and the incidence of various arrhythmia in patients diagnosed with ST-Elevation Myocardial Infarction (STEMI). Methodology: A prospective observational cohort study was conducted among 55 patients who present to the hospital within 12 hours of the onset of symptoms of STEMI at tertiary care center where Magnesium levels were evaluated for the occurrence of arrhythmias. Results: The age of the patients ranged from 35 to 79 years, with the majority being older than 65 years, and an equal distribution of males (50.91%) and females (49.09%). Common risk factors included hypertension (47.27%) and diabetes mellitus (54.55%). The results of the study indicated a statistically significant association between lower magnesium levels and the occurrence of arrhythmias in STEMI patients. Patients with arrhythmias had a mean serum magnesium level of 1.44 mg/dL, compared to 1.89 mg/dL in those without arrhythmias (p < 0.05). Conclusion: Patients diagnosed with ST-Elevation myocardial Infarction who had lower magnesium levels (<1.6 mg/dL) demonstrated a higher incidence of arrhythmias, particularly ventricular fibrillation and atrial fibrillation, compared to those with normal magnesium levels (1.6?2.4 mg/dL). This statistically significant association highlights the crucial role of magnesium in maintaining cardiac electrical stability during acute myocardial infarction.
Keywords: Ischemic heart diseases, STEMI, magnesium levels, arrhythmias
Edition: Volume 14 Issue 2, February 2025
Pages: 1372 - 1376
DOI: https://www.doi.org/10.21275/SR25221154859
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