Downloads: 119 | Views: 290 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Research Paper | Pharmacology Science | India | Volume 4 Issue 4, April 2015 | Popularity: 6.7 / 10
Evaluation of Antimitogenic and Cytotoxic Potential of Anacardiumoccidentale Leaf Extracts in Allumcepa Root Tip Cells and Against Sarcoma-180 Cells
Pralay Maity, Madhubanti Bepari, Sujata Maiti Choudhury
Abstract: Anacardium occidentale of family Anacardiaceae is a tropical tree and used traditionally for the treatment of different diseases. In the present study, we have evaluated the anti-mitotic and cytotoxic activities of ethanolic (EEAOL), methanolic (MEAOL) and water (WEAOL) extracts of Anacardium occidentaleleaf in Allium cepa root tip cells and against Sarcoma-180 cell lines. Ethanol, methanol, and water extracts were prepared from pulverized powder obtained from shed-dried leaves of Anacardium occidentale. The antimitotic activity was measured using Allium cepa root meristematic cells. The studies were extended to Sarcoma-180 cell lines to obtain the cytotoxic potential of the plant. Anacardium occidentaleextracts were found to be antimitotic for Allium cepa root tip cells at the concentration of 100mg/ml and also exhibited in vitro cytotoxicity against Sarcoma-180 cell lines at100 g/ml concentration. These findings reveal that Anacardium occidentaleleaf possesses pronounced antimitotic and cytotoxic potential in Alliumcepa root and against Sarcoma-180 cell lines.
Keywords: Anacardium occidentale, Allium cepa, S-180 cell, Antimitotic, Cytotoxic
Edition: Volume 4 Issue 4, April 2015
Pages: 290 - 293
Make Sure to Disable the Pop-Up Blocker of Web Browser
