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Case Studies | Pathology | India | Volume 4 Issue 6, June 2015 | Popularity: 6.6 / 10

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Melanotic Neuroectodermal Tumor of Infancy, A Rare Pediatric Tumor: Report of Two Cases with Review of the Literature

Neeraj Dhameja, Ravi Bhushan Raman, Vijay Kumar Jha, Abhijeet Kunwar

Abstract: Melanotic neuroectodermal tumour of Infancy is a rare pediatric tumour with benign course and favourable prognosis. There are very few cases described in the literature. Herein, we report two cases of melanotic neuroectodermal tumour in infants, one with right maxillary mass and other with left temporal region swellings. Both the cases were diagnosed initially on fine needle aspiration cytology that revealed dual population of small cells and large epithelial cells with brownish black pigment. Later, histopathological examination showed characteristic morphological features with smaller neuroblastic cells and larger pigmented epithelial cells. Immunohistochemistry showed positivity for epithelial, melanotic and neural markers in various components of tumour.

Keywords: Melanotic neuroectodermal tumour of infancy, Maxilla, Temporal region, Fine needle aspiration cytology, Immunohistochemistry

Edition: Volume 4 Issue 6, June 2015

Pages: 1058 - 1060

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