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Survey Paper | Medicine Science | Bulgaria | Volume 4 Issue 6, June 2015 | Popularity: 6.7 / 10

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Clinical and Computed Tomography Studies of Parkinson's Disease

Manchev Lachezar, Mancheva-Ganeva Velina, Manchev Ivan, Traikova Nikoleta, Groudeva Violeta

Abstract: 293 patients suffering from Parkinsons disease were studied. In 230 of them a Computed Tomography (CT) scan of the brain was performed. The scan found pathological abnormalities in 95 patients (49 men and 46 women). The basic clinical symptoms were studied as well, while the patients condition was assessed by specialized scales (UPDRS, Hoehn and Yahr, Schwab and ngland). Electromyography studies of tremor were conducted as well. Tremor found in 274 patients (91, 3 %), hypomimia found in 268 patients (91, 4 %) and lack of motivation/initiative found in 245 patients (83, 6 %) were the most frequent clinical manifestations. The modified Hoehn and Yahr scale showed that the mild to moderate bilateral pathological changes, ranging between 2, 5 and 3 stages, were most frequently found, while the Schwab and England scale revealed that 40, 9 % of the patients were completely independent in their every day household activities, but they needed twice as much time to perform them. The pathological CT scan results showed a significant correlation with the severity of the clinical symptoms, assessed by the Hoehn and Yahr scale, a fact which makes the combination of these two methods particularly appropriate for clinical assessment of patients, suffering from Parkinsons diseases.

Keywords: Parkinsons disease, Hoehn and Yahr Scale, Computed tomography

Edition: Volume 4 Issue 6, June 2015

Pages: 1463 - 1467

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