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Research Paper | Microbiology | Nigeria | Volume 4 Issue 7, July 2015 | Popularity: 6.6 / 10

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A Comparative Analysis of Multi-Drug Resistance Patterns in Pseudomonas Aeruginosa Isolated From Environmental Sources in Auchi, Edo State, Nigeria

Dania U. J., Ojokoh A. O.

Abstract: This study investigates the rate of sensitivity of multi-drug resistant P. aeruginosa from various environmental sources. A total of 72 Pseudomonas aeruginosa was obtained from the environmental sources which are waste water, soil and air. Isolated pure cultures of bacteria were subjected to various morphology and biochemical tests. The antibiotic susceptibility test was performed using disc diffusion method. Twelve (12) clinical pertinent antibiotics (Augmentin (Aug), Cloxacillin (Cxc), Gentamicin (Gen), Amikacin (Amk), Ceftazidime (Caz), Cefuroxime (Crx), Cetriazone (Ctr), Ciprofloxacin (Cpr), Ofloxacin (Ofl), Erythromycin (Ery), Imipenem (Imp) and Meropenem (Mer)) were tested against P. aeruginosa. Variation occurred in multidrug resistance patterns among various strains of Pseudomonas aeruginosa isolated. Among the antibiotics, the most effective were meropenem (carbepenems) and amikacin (aminoglycosides) with their resistant rate as 26.39 % and 43.06 %, respectively while the least effective were cloxacillin (penicillin) and cefuroxim (cephalosporin) both with resistant rate of 100 % among the 72 P. aeruginosa strains. Six isolates were resistant to all the twelve antibiotics used. This study has shown that there is wide spread antimicrobial resistance patterns of some environmental strains of Pseudomonas aeruginosa from Auchi in Edo state, Nigeria.

Keywords: Pseudomonas aeruginosa, Multi-drug, Susceptibility, Environmental sources, Auchi, Edo, Nigeria

Edition: Volume 4 Issue 7, July 2015

Pages: 2068 - 2072

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