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Research Paper | Anaesthesiology | India | Volume 13 Issue 5, May 2024 | Rating: 4.8 / 10

A Comparative Study on Two Doses of Esmolol 0.5mg/Kg and 1.5mg/Kg to Attenuate the Hemo Dynamic Stress Response during Laryngoscopy and Endo Tracheal Intubation

Dr Subramanya K | Dr Kilaparthi Teja | Dr Karuna Kumar Das

Abstract: This study investigates the optimal dose of esmolol to attenuate the hemodynamic response to laryngoscopy and endotracheal intubation. Conducted over six months at a tertiary healthcare center, 40 patients undergoing general surgical procedures were divided into two groups receiving either 0.5 mg/kg or 1.5 mg/kg of esmolol. Heart rate and blood pressure were monitored at baseline, during, and after intubation. The results showed that a 1.5 mg/kg dose of esmolol significantly reduced the increase in heart rate and blood pressure compared to the 0.5 mg/kg dose. The higher dose was more effective in minimizing the hemodynamic stress response, with no major side effects reported.

Keywords: Esmolol, Hemodynamic response, Laryngoscopy, Endotracheal intubation, Beta-blockers

Edition: Volume 13 Issue 5, May 2024,

Pages: 999 - 1002