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Comparative Studies | Medical Science | Volume 8 Issue 10, October 2019 | Pages: 1523 - 1528 | India
Randomized Comparative Study to Evaluate the Effectiveness of Ropivacaine 0.125% Versus 0.2% with Fentanyl in Epidural Labor Analgesia
Abstract: Background: Minimum effective concentration of local anesthetics for providing optimal labor epidural analgesia and the strategies aiming to reduce their consumption are continuously being searched. Objectives: The objective of this study was to evaluate the efficacy of 0.125 % and 0.2 % ropivacaine both mixed with fentanyl 2 mcg/ml for epidural labor analgesia. Materials and Methods: A total of 80 parturients in active labor were randomly assigned to two groups of 40 each, to receive an epidural injection of 15 ml ropivacaine 0.125 % with fentanyl (2 mcg/ml) in group R1 and 15 ml of ropivacaine 0.2 % with fentanyl (2 mcg/ml) in group R2 as initial bolus dose. Same dose regimen was used as subsequent top-up dose on patients demand for pain relief. The duration and quality of analgesia, motor block, top-up doses required consumption of ropivacaine and fentanyl and feto-maternal outcome in both groups were compared. Results: Effective labor analgesia with no motor blockade was observed in both groups with no failure rate. Onset of analgesia was significantly faster in group R2 (75 % parturients in 0-5 min) as compared to group R1 (25 % parturients in 0-5 min), P 0.05), but consumption of fentanyl was significantly more in group R1 (54.00 19.45) as compared to group R2 (31.50 6.62), P
Keywords: Epidural labor analgesia, labor analgesia, ropivacaine 02 % versus 0125 %, fentanyl
How to Cite?: Dr Krishna, Dr. Athyun, "Randomized Comparative Study to Evaluate the Effectiveness of Ropivacaine 0.125% Versus 0.2% with Fentanyl in Epidural Labor Analgesia", Volume 8 Issue 10, October 2019, International Journal of Science and Research (IJSR), Pages: 1523-1528, https://www.ijsr.net/getabstract.php?paperid=ART20202188, DOI: https://dx.doi.org/10.21275/ART20202188