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Case Studies | Cancer Science | India | Volume 13 Issue 2, February 2024 | Rating: 4.5 / 10

The Reports of Cleft Patients from 2023-2024 and its Possible Link, Discussions and its Search for a Minimal Therapeutic Alternatives Still Remains

Abstract: Clefts being the commonest craniomaxillofacial disorders today can be due to multifactorial reasons which need further studies. In this article, we report a case of multiple cleft patients done under mission smile (India) where the commonest possible link being nutritional deficiency in a mother and second being a father who had history of alcohol intake. Still, further study is needed whether cleft etiology on a cell level is directly link to either just a single mother or her habits or link to both the parents. Do the father genes play an important role and does alcohol intake really affect the child. Why cleft occurs in just the lip and palatal area. Is it because there is suture or is it because of the cells that are more prone to nutritional deficiency. Suture are also present in the other facial skull bones but somehow cleft seems to occur in mostly the lip and palatal region which might be due to nutritional, cell, genetic and environmental habits that a child does during pregnancy while feeding which needs further studies.

Keywords: craniomaxillofacial, retinol, cadherin, multifactorial

Edition: Volume 13 Issue 2, February 2024,

Pages: 531 - 532