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Study Papers | Pediatrics | India | Volume 12 Issue 3, March 2023 | Rating: 4.8 / 10
Clinical Spectrum of Tuberculosis in BCG Vaccinated Children
Dr. Arunasri Navuluri
Abstract: Objectives: This study was undertaken to evaluate the clinical spectrum of Tuberculosis in properly BCG vaccinated children in age group of 2months to 12 years. 1. To study the clinical presentation of Tuberculosis in BCG vaccinated children aged between 2 months-12 years. 2. To study the various complications and sequelae of the disease. Methods: This prospective study was conducted in the Department of Pediatrics-Children in the age group from 2 months to 12 years attending the Outpatient Department, admitted in the wards or in the PICU with symptoms suggestive of Tuberculous disease were subjected for detailed evaluation. Asymptomatic children close contact with adult Tuberculous patients were also investigated and included in the study if found to have Tuberculous disease. All with BCG scar were included in this study. Results: 159 children who fulfilled the diagnostic criteria for Tuberculous disease were initially included in the study but final analysis was done in only 104patients who could be completely followed up. Maximum number of cases were in the 1 to 5 years age group 43 (41.34%), 29 (27.88%) were in 6 to 10 years age group, 18 (17.34%) were under I year and 14 (13.46%) were in the age group 11 to 12 years. The present study shows predominant symptoms of presentation are Fever 68 (65.38%) and cough 61 (58.65%). 38 (36.53) had initial presentation as seizures. One third had weight loss or poor weight gain, Significant lymph-adenopathy was observed in 28 (26.92% 0 cases and 14 (13.46% 0 has wheezing. Statistically significant relation was observed between severe forms of tuberculosis and PEM. Conclusion: All types of TB occur in properly BCG vaccinated children and 33.65% progress to severe disseminated forms. Maximum number of cases were in the 1 to 5 years age group 43 (41.34%). Our study reveals that protective benefit of BCG vaccine against the dissemination of tuberculosis in children is possible only if they have normal nutrition and improved socio-economic conditions.
Keywords: Tuberculosis, BCG, Socio economic status, Nutrition
Edition: Volume 12 Issue 3, March 2023,
Pages: 738 - 740