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Dissertation Chapters | Medicine Science | Albania | Volume 4 Issue 11, November 2015 | Rating: 6.8 / 10
Evaluation of Red Cell Transfusion Effects on Tissue Oxigenation, Based on Blood Lactate Levels As Sensitive Indicator of Tissue Oxygenation
M. Lordian Nunci [2] | Ilir Ohri Chef | Edi Grabocka [2]
Abstract: Purpose Evaluation of red cell transfusion effects on tissue oxygenation, by measuring blood lactate levels before and and after hemotransfusion. Blood lactate level are suggested as sesitive parameter to evaluete tissue oxigenation. The aim of this stydy was to verify the efficiency of hemotransfusions that were performed on patients in intensiv care based on lactate level. Study design Prospective observational Methods In this prospective observational stydy on (n- 59 patients) who considered that required red cell transfusion. (the patients more that 25 point according to APACHE II-score were excluded). We monitor vital sings (BP, HR) at addmision and also was stictly observed lactate level and hemoglobin level at addmision before red cell transfusion (pre T), two hours after transfusion (2h post T) and 24 hours after (24 h post T with or no any another red cell transfusion). At first the patients group based at hemoglobin level, Group Ia with Hb< 8g/dl and Group IIb with Hb - 8g/dl. After that the patients group again based at lactate level, Group Ic lactat level - 2, 4 and Group IId lactate level <2, 4. Results Comparison between group Ia and group IIb as belongs hemoglobin level demonstrate significance only at addmision pre T and lost significance at 2h post T and 24h post T, at the other hand differences between group Ic and gropIId as belongs hemoglobin level stay significant at pre T, 2h post T and 24h post T Conclusions Statistical significant evaluation (p < 0, 05) between above mentioned groups shown that lactate level are very sensitive indicator in measuration of tissue oxygenation. . Another important finding was significant high mortality and morbidity at patient group with lactate level - 2, 5.
Keywords: red cell transfusion, lactat level, hemoglobin level, oxygenation, anemia
Edition: Volume 4 Issue 11, November 2015,
Pages: 815 - 821