Anthelmentic Effect of Ethanol Leaves and Hexane Seed Extarction of Capparis Spinosa on Earth worm Motility and Echinococcus Granulose Protoscolices, in Kurdistan Region, Iraq

Lokman T. Omer Al-Barwary

Abstract: The present study was conducted to assessment in-vitro anthelmintic activity of ethanolic and hexane extract from leaves and seed of plant Capparis spinosa. The anthelmintic activity of plant leaves and seed is investigated through using earthworm (Lumbricus terrestris) and on viability of protoscolices Echinococcus granulosus. Various concentrations of ethanol (leaves) and hexane (seeds) extract (200 and 300 mg/ml) from both extract of capparis spinosa were tested, for determination of death and paralysis time, and 5, 10, 20 mg/ml for both extract for assessment mortality percentage protoscolices Echinococcus granulosus and fenbendazole was included as reference standard. The mortality of protoscolies with both extract after 2hr reach 90-100 %, however, the results related that the leave extract was more effective on the motility of earth worms, since the paralysis occurs after 8.5 minutes and death 21 minutes during using 200mg/ml. and the time need to paralysis and death occurs by using 300mg/ml after 7.3minutes and 18 minutes respectively. The results of study indicate, that plant Capparis spinosa, possesses strong anthelmintic activity

Keywords: Capparis spinosa, Lumbricus terrestris earth worms, protoscolices Echinococcus granulosus