Correlation Of Spot Urine Protein Creatinine Ratio With Angiographic Disease Severity In Non-Diabetic Stable Coronary Artery Disease

Raghuram Bollineni, Durgaprasad Rajasekhar, Vanajakshamma Velam, Harini Devi N

Abstract: Background: Coronary artery disease (CAD) is a major cause of death and disability. Microalbuminuria, a marker of atherogenesis and early endothelial damage has been an emerging risk factor. This study aimed to correlate urine spot protein creatinine ratio with angiographic disease severity in non-diabetics with stable coronary artery disease. Methods: This was a single center prospective observational study which included 100 non-diabetic patients with stable CAD. Spot urine protein creatinine ratio was used to define Microalbuminuria (MA) (30-300mg/g creatinine), and severity of CAD was estimated using SYNTAX score and Modified Gensini score. Patients were divided into two groups: one group included patients with out MA and another group included patients with MA. Results: Out of 100 non-diabetic patients with stable coronary artery disease, 56 (56 %) were in MA negative group and 44 % were in MA positive group. The mean age of the study population was 58.65±9.7 years with majority of them being males (75 %). The prevalence of double vessel CAD and triple vessel CAD was significantly higher in MA positive group compared with the MA negative group (79.54 % vs 26.78 % p

Keywords: Coronary artery disease, Microalbuminuria, SYNTAX score, Modified Gensini score

How to Cite?: Raghuram Bollineni, Durgaprasad Rajasekhar, Vanajakshamma Velam, Harini Devi N, "Correlation Of Spot Urine Protein Creatinine Ratio With Angiographic Disease Severity In Non-Diabetic Stable Coronary Artery Disease", Volume 9 Issue 4, April 2020, International Journal of Science and Research (IJSR), Pages: 934-937, https://www.ijsr.net/getabstract.php?paperid=SR20413210226, DOI: https://dx.doi.org/10.21275/SR20413210226

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