A Rare Case Report on Pregnancy in Patient of Glanzmann's Thromasthenia

Dr. Shirish Toshniwal, Dr. Ajesh N. Desai, Dr. Fenuka Patel

Abstract: Glanzmann's thrombasthenia is a congenitally acquired platelet disorder with an autosomal recessive mode of inheritance. Though, quantitatively normal, the aggregation ability of platelets is reduced in this condition. Pregnancy and delivery are rare in these patients and have been associated with a high risk of severe postpartum haemorrhage. We describe a primigravida, who was diagnosed to have Glanzmann's thrombasthenia during adolescence. Patient was admitted with labor pain due to meconium - stained liquor after induction of labor emergency caesarean section was done. which was successfully managed by platelets and single donor platelet transfusion.

Keywords: Glanzmann's thrombasthenia, inherited disorder, platelet disorder