Downloads: 3 | Views: 277 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1

Informative Article | Dermatology | India | Volume 11 Issue 5, May 2022 | Popularity: 5.1 / 10

Rate This Article!      

Calcific Uremic Arteriolopathy (Calciphylaxis) Dermatological Case

Dr. Nikhat, Dr. Sumera Huma

Abstract: Introduction: Calciphylaxis, also known as calcific uraemic arteriolopathy (CUA), is a rare condition characterized by exquisitely painful necrotic ulcerations in patients with end-stage renal disease (ESRD) undergoing dialysis. Calcific uraemic arteriolopathy can be characterized by obstructive vasculopathy, with calcification of small arteries and arterioles resulting in luminal occlusion and subsequently cutaneous necrosis [1]. The incidence of CUA is estimated to be approximately 1% in patients with CKD and 4% in patients on dialysis [2]. The disease is rare but devastating, increasing in dialysis population [3] and its aetiology is still unmasked that is challenging demonstrates a challenge for different specialities. Even if diagnosed in early stages, the mortality rate remains exceptionally High and the success in healing is low. [4] Mortality rates are estimated at 60-80% [5]Furthermore, the disease is characterized by skin ulceration that undergo necrosis leading to intense pain and can be localized on any part of the skin. Objective: To raise awareness of Calciphylaxis in hopes of prompting earlier recognition with improved clinical outcomes. It is a rare complication but a fatal event of chronic kidney disease.

Keywords: Calcific Uremic Arteriolopathy, Calciphylaxis, Dermatology

Edition: Volume 11 Issue 5, May 2022

Pages: 1818 - 1820

DOI: https://www.doi.org/10.21275/SR22524002442

Make Sure to Disable the Pop-Up Blocker of Web Browser

Click to Cite this Article

Similar Articles