Downloads: 2 | Views: 128 | Weekly Hits: ⮙2 | Monthly Hits: ⮙2
Study Papers | Medical Science | India | Volume 12 Issue 12, December 2023 | Popularity: 5.2 / 10
Study of Fractional Exhaled Nitric Oxide among Chronic Obstructive Pulmonary Disease Patients in Acute Exacerbation
Dr. Madhurima A. S., Dr. Priti Meshram, Dr. Vishwanath Pujari, Dr. Rohit Hegde
Abstract: Context and Background: FeNO helps in detection and monitoring of eosinophilic airway inflammation, determining the likelihood of corticosteroid responsiveness and the potential need for the same in treatment. The role in asthma, where increased FeNO reflects eosinophilic mediated inflammatory pathways in central and/or peripheral airway sites and implies increased inhaled and systemic corticosteroid responsiveness has been extensively studied. COPD being a non-eosinophilic inflammatory condition, steroids are considered to have minimal role in the management of stable disease. The aim of this study is to determine whether FeNO rises in an acute exacerbation of COPD and the demographic characteristics related to the same. Methods: A total of 100 COPD patients in exacerbation who were able to perform FeNO were evaluated with detailed history and physical examination, complete and differential blood count and spirometry. Patients? FeNO was measured after admission using a portable hand-held machine called NO-BREATH in the sitting position. Those patients with active tuberculosis or other significant comorbidities and unable to perform FeNO were excluded along with those on immunosuppressants. Results: With mean age of 58.5 years, 68% patients of the study population had insignificant FENO levels (less than 25 ppb), 31% between 25-50ppb (indeterminate levels) and only 1 patient above 50 ppb. 92% patients had normal blood eosinophils and 73% had raised blood neutrophils. Smoking was the most common risk factor (97%) with a mean smoking index -436.4. Conclusion: Most patients of COPD exacerbation in this study had insignificant FENO levels. Smoking in males and exposure to noxious stimulants in females was the commonest risk factor for COPD.
Keywords: FeNO, Chronic Obstructive Pulmonary disease, Eosinophils, ACOS
Edition: Volume 12 Issue 12, December 2023
Pages: 1524 - 1528
DOI: https://www.doi.org/10.21275/SR231219220032
Make Sure to Disable the Pop-Up Blocker of Web Browser
Similar Articles
Downloads: 0
Research Paper, Medical Science, Serbia, Volume 11 Issue 5, May 2022
Pages: 1229 - 1231COVID-19 Related "Pneumo" Complications: Regional Hospital Experience
Sladjana Radosavljevic, Aleksandra Plecas Djuric, Jelica Alargic, Dusanka Obradovic
Downloads: 0
Case Studies, Medical Science, Indonesia, Volume 11 Issue 10, October 2022
Pages: 252 - 255Association of the Neutrophil-Lymphocyte Ratio with Lung Function in Patients with Chronic Obstructive Pulmonary Disease at RSUD Sanjiwani Gianyar 2022
Ni Putu Intan Hapsari, Putu Dyah Widyaningsih
Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Research Paper, Medical Science, Indonesia, Volume 12 Issue 3, March 2023
Pages: 1143 - 1148Upper Extremity Strength Training Effectiveness on COPD Patients? Muscle Mass Using Home - Based Pulmonary Rehabilitation
Fifi Maylida. S, Amira Permatasari Tarigan, Pandiaman Pandia, Putri Chairani Eyanoer
Downloads: 1 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Research Paper, Medical Science, India, Volume 12 Issue 11, November 2023
Pages: 1376 - 1382An Observational Study to Asses the Echocardiographic Changes in Chronic Obstructive Pulmonary Disease
Dr. A. K. Shadani, Dr. Pegada Dhanlakshmi, Dr. R. Gupta
Downloads: 2 | Weekly Hits: ⮙1 | Monthly Hits: ⮙1
Student Project, Medical Science, India, Volume 13 Issue 5, May 2024
Pages: 1089 - 1093Effectiveness of Segmental Breathing Exercise Versus Respiratory Muscle Stretches on Dyspnea and Exercise Tolerance Level among COPD Patients
S. Aravind, P. Senthil Selvam