International Journal of Science and Research (IJSR)

International Journal of Science and Research (IJSR)
Call for Papers | Fully Refereed | Open Access | Double Blind Peer Reviewed

ISSN: 2319-7064




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Research Paper | Obstetrics and Gynecology | India | Volume 12 Issue 5, May 2023 | Rating: 4.6 / 10


Evaluation of Ovarian Tumours using International Ovarian Tumour Analysis (IOTA) Simple Ultrasound Rules and its Correlation with Histopathological Examination

Shweta Bharti | Ranjana [49] | Neeru Goel | S. K. Suman


Abstract: The study aimed to evaluate the diagnostic accuracy of IOTA simple ultrasound rules for the differentiation of ovarian tumors. A total of 100 patients suspected of ovarian pathology either by pelvic examination or by the previous ultrasonographic report were included in the study. The patients were assessed using IOTA simple rules at the time of the first visit by a resident physician in the department of OBGY followed by an expert sonologist in the radiology department by transabdominal sonography. Patients were assessed by histopathological investigations. The mean age of the patients was 35.55?13.9 years. According to IOTA simple rules 20 were malignant, 58 were benign and 22 ovarian masses were inconclusive. A total of n=67 patients had surgery of which 19 were malignant, 26 were benign and 22 were indeterminate. Kappa statistics showed a high level of agreement between expert (Sonologist) and non - expert (Resident of Obstetrics and Gynaecology) in diagnosing benign tumour (k = 1, 100%) and malignant tumour (k = 0.968, 96.8%) with P value less than 0.05. The sensitivity and specificity of the IOTA simple rules in predicting malignant ovarian mass were 93.33% and 83.33% respectively. Positive predicting value (PPV) and Negative predictive value (NPV) were 73.68% & 96.15 % respectively. After considering indeterminate mass as malignant mass and all followed - up cases as benign as those all were benign at a follow - up visit, sensitivity, specificity, PPV and NPV were 94.4%, 69.51%, 40.47%, and 98.27% respectively. IOTA simple ultrasound rules are effective in classifying ovarian masses as benign and malignant masses and can be used by both experts and non - experts with good accuracy.


Keywords: Benign ovarian cancer, IOTA simple rules, Malignant ovarian cancer, Ovarian cancer


Edition: Volume 12 Issue 5, May 2023,


Pages: 2549 - 2553



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