Development of Extractive Spectrophotometric Method for the Determination of Copper (II) with Schiff Base 2-{(E)-[(2, 4-dichlorophenyl) imino] methyl } -6-methoxyphenol

Nitin Kadam, Ritika Makhijani

Abstract: Using 2-(E)-[(2,4-dichlorophenyl)imino]methyl-6-methoxyphenol [DCPIMMP], a robust spectrophotometric technique has been devised to measure copper (II). DCPIMMP extracts quantifiable amounts of Cu(II) into chloroform from an aqueous solution with a pH between 3.9 and 5.9. The chloroform extracts show maximum absorption at 590 nm(?max). Beer?s Law is obeyed over the Cu (II) concentration range of 0.5 to 20.0 ?g/ml. The Molar absorptivity and Sandell?s sensitivity for Cu?DCPIMMP system is 3559 L mol -1 cm-1 and 0.018?g cm-2respectively. The composition of extracted species is found to be 1: 2 [Cu-DCPIMMP] by Job?s continuous variation and Mole-ratio method. Interference by various ions has been studied. The proposed method is rapid, sensitive, reproducible and accurate and it has been satisfactory applied for the determination of Copper in Pharmaceutical Samples.

Keywords: Solvent Extraction, Extractive Spectrophotometry, Copper (II), Schiff base, 2-{(E)-[(2,4-dichlorophenyl)imino]methyl}-6-methoxyphenol [DCPIMMP], Pharmaceutical sample