Comparative Analysis of DysphagiaOptimized IMRT vs Standard IMRT in Oral Cavity Cancer Treatment: A Single - Center Study

Ramyavardhani Mamidala, Prathipati Navyasri, Kotlapati Sudhakar, Jyothi Jonnadula, Prattipati Srinivas, Thota Ajay

Abstract: Objective: This study investigates the efficacy of Dysphagia Optimized Intensity Modulated Radiotherapy (Do - IMRT) compared to Standard Intensity Modulated Radiotherapy (S - IMRT) in managing dysphagia and overall treatment efficacy among patients with oral cavity cancers treated at the Department of Radiation Oncology, Kamineni Academy of Medical Sciences and Research Centre, Hyderabad. Methods: We enrolled 300 patients diagnosed with oral cavity cancers from July 2022 to July 2024, randomly assigning them to either the Do - IMRT group (n=150) or the S - IMRT group (n=150). Dysphagia severity was assessed using the Dysphagia Severity Rating Scale (DSRS) at baseline, during treatment, and at a 6 - month follow - up. Treatment outcomes, including overall survival rates and treatment - related toxicities, were analyzed. Results: Patients treated with Do - IMRT demonstrated significantly reduced dysphagia, as evidenced by lower DSRS scores during treatment and at 6 months post - treatment (p

Keywords: Dysphagia, Optimized Intensity Modulated Radiotherapy (Do - IMRT), Standard Intensity Modulated Radiotherapy (S - IMRT), Oral Cavity Cancer, Single - Center Study

How to Cite?: Ramyavardhani Mamidala, Prathipati Navyasri, Kotlapati Sudhakar, Jyothi Jonnadula, Prattipati Srinivas, Thota Ajay, "Comparative Analysis of DysphagiaOptimized IMRT vs Standard IMRT in Oral Cavity Cancer Treatment: A Single - Center Study", Volume 13 Issue 10, October 2024, International Journal of Science and Research (IJSR), Pages: 644-647, https://www.ijsr.net/getabstract.php?paperid=SR241006095215, DOI: https://dx.doi.org/10.21275/SR241006095215

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