CRIB-II Score as an Indicator of Neonatal Morbidity among Preterm Neonates: A Prospective Observational Study

Dr. Sahana G, Dr. Matta Sai Kiranmai, Dr. Adarsh E

Abstract: Advancements in the Neonatal Intensive Care with scoring systems like Clinical Risk Index for Babies-II(CRIB_II) to stratify sick new-born have decreased both morbidity and mortality. This study assessed the ability of CRIB-II score to predict neonatal morbidity and survival. A prospective observational study was conducted among 42 (21 male and 21 female) preterm neonates admitted within 12 hours of birth in a tertiary care hospital. Antenatal, perinatal variables, respiratory support, CRIB-II score and neonatal morbidity of the neonates were recorded. Association tests and Receiver operating characteristics curve analysis were performed. The mean birth weight and gestational age were 1226?229grams and 30.12?1.4weeks respectively. All had ocular complication, while 31%, 12%, 9.5% and 4.8% had neurological morbidity, sepsis, cardiac abnormality and pulmonary manifestations respectively. Mean CRIB-II score was 6.60?6.739. AUC in predicting the neonatal morbidity for CRIB-II score was 0.777 (p- 0.004) at cut-off value of ? 9 significant with 89.7% specificity. The cut-off value for predicting both the neonatal mortality and neurological morbidity was ? 9 with specificities of 92% and 87% respectively. This study concluded that CRIB-II had better discriminating ability in predicting any neonatal morbidities and better diagnostic acumen in predicting cardiac and neurological morbidities.

Keywords: Neonatal risk scoring system, Prenatal morbidity, Prenatal mortality, Preterm neonates